Athanasios Karapetsas

Athanasios Karapetsas, MSc. PhD.


Athanasios (Thanos) Karapetsas was born in Athens, Greece and graduated from the Department of Molecular Biology and Genetics, Democritus University of Thrace in Alexandoupolis, Greece (2008). He obtained a Master’s degree in Pharmacology and Therapeutics (2010) and then he went on to do a PhD in Molecular Biology at the Department of Department of Molecular Biology and Genetics in Greece where he studied the molecular mechanisms underlying T-lymphocyte infiltration in early stage ovarian cancer (2014). Following, he worked as a postdoctoral researcher studying the health promoting properties of probiotics and natural products in disease models. In order to develop new skills, in 2016 Thanos moved to Dundee (UK) to join the laboratory of Prof. Dario Alessi at the MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee as a postdoctoral research assistant. He is currently investigating the function and regulation of the SGK3 protein kinase, a kinase that bears high similarity to Akt, gets upregulated upon prolonged treatment of breast cancer cells with PI3K or Akt inhibitors and substitutes for Akt. Thanos identified and validated the first selective SGK3 substrates, namely Syntaxin 7 and Syntaxin 12, and explored the biological role of this phosphorylation. Thanos’s main research interest is the elucidation of signaling pathways in health and disease, with a focus on cancer.

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